High Desert Heart Institute Study

The results of the High Desert Heart Institute Study have the potential to change the way cardiovascular issues are treated.  Why?  Because this study clearly showed the importance of addressing the health needs of your endothelium and how improving its health affects your cardiovascular system.

One of the organs within your body that is greatly affected as you age is the endothelium that lines all of your cardiovascular system.  The endothelium is made up of endothelial cells.  It’s important to note that these cells line the entire circulatory system from the heart all the way down to the smallest capillary. Once thought to have very little functional use, research has shown that the endothelial cells are critical to cardiovascular health as well as your overall wellness.

This study was conducted at the High Desert Heart Institute, which is located in Victorville, California. This institute is one of the most prestigious heart institutes in the United States and their groundbreaking study is beginning to draw international attention.  Why?  Because the data collected seems to support the convictions of Dr. J. Joseph Prendergast and the 1998 Nobel Prize Laureate in Medicine Dr. Louis J. Ignarro. Their conviction is that heart disease can be prevented and reversed when a proper L-Arginine / L-citrulline protocol is used to repair and enhance the endothelial cells ability to properly produce nitric oxide, the master signaling molecule of the cardiovascular system.

The purpose of this page is to provide you with an overview of this landmark, 90-day, human clinical study. It will introduce you to the major contributors to this study, provide you with a general overview of the study, and willcollect additional information and videos concerning this study.

General Overview of the High Desert Heart Institute Study!

During the early part of 2009 a 90-day human clinical study was started at the High Desert Heart Institute.  This study started with 35 congestive heart failure patients who were from the Congestive Heart Failure Unit at the institute.  It concluded in July of 2009 with 33 patients.  One patient dropped out because they received a new heart.  The other patient dropped out because they were not able to remain compliant to the study’s protocols.

Over the course of the 90-day study, each patient received extensive diagnostic testing which generated approximately 7,000 points of data. Some of the tests used to generate this data were:

The patients chosen for this study had all reached their maximum pharmacological and medical management, and there was nothing further that could be done for them outside of a heart transplant.  Prior to the start of this study 60% of these patients were on a heart transplant list.  Each patient was given 2 scoops of ProArgi-9 Plus in the morning and 2 scoops of ProArgi-9 Plus in the evening for 90 days. Each scoop of ProArgi-9 Plus contains 5 grams of pharmaceutical grade L-Arginine as well as several other ingredients that support nitric oxide production and heart health.

The outcome of this study was “remarkable!”  All patients were removed from the heart transplant list. All patients were able to eliminate or greatly reduce the drugs they were taking.  All patients were able to recover normal lives.

Prior to the study’s publication, the following general statement was made by Dr. Siva Arunasalam who helped direct and supervise this study:

“There was nothing else for us to try, we had tried everything with these patients.  All patients showed a tremendous improvement in many, many objective data points that only can be attributed to ProArgi-9. . .”

Dr. Siva also made the following significant comment:

“… but what we ended up seeing was remarkable positive remodeling of the heart, positive pulmonary artery changes, pulmonary vascular changes in terms of pulmonary pressures, changes in the cardiac dimensions, changes in heart function …”

Because of the success of this study, the High Desert Heart Institute has formally implemented an L-Arginine / L-Citrulline protocol using the ProAgri-9 Plus as part of their routine standard of care for all patients.

Major Contributors

High Desert Heart Institute – This institute is located in Victorville, California and provides primary care and heart disease services in an outpatient setting.  This outpatient center provides all of the routine heart tests such as electrocardiography, event monitoring, Holter monitoring, and routine blood tests.  In the area of advanced diagnostic and therapeutic methods, this institute provides in-house echocardiography, vascular ultrasound, nuclear stress testing, pulmonary function testing as well as a variety of other important diagnostic modalities.  This is the first outpatient center in the High Desert area to provide EECP (Enhanced External Counter Pulsation) which is an important therapy for those patients with angina and heart failure.

Dr. Siva Arunasalam – Dr. Siva (as he prefers to be called) is the Founder and Director of the High Desert Heart Institute.   He authorized this study and paid for all the testing and patient care.  Dr. Siva completed his cardiology training at Cedars-Sinai Medical Center in Los Angeles.  He was recruited by St. Mary Regional Medical Center to bring advanced cardiac care technology to the High Desert area.  Initially the Institute started in a small office near the hospital but had explosive growth requiring a move to a larger facility.  Because of the excellent care and treatment patients receive, the Institute is in the process of building an even larger facility on Hesperia Road so that it can better care for and service patients as well as incorporate more specialists into their operation.

Dan Austin, RN – Dan is the director of the Congestive Heart Failure Unit at the High Desert Heart Institute.  He helped design this study and was the RN in charge of every patient in this study.

Click on the player below to listen to Dr. Siva and Dan Austin as they give their first extensive interview regarding this landmark clinical study!

[audio:http://www.vt-us.net/co-op/audio/dr-siva-testimony.mp3]
ProArgi-9 Plus – This is the nutritional supplement used in this groundbreaking study.  This product is formulated by Dr. J. Joseph Prendergast and manufactured by Synergy WorldWide.  It contains 5 grams of pharmaceutical grade L-Arginine plus several other ingredients that support nitric oxide production and heart health.

Dr. J. Joseph Prendergast – Dr. Joe (as he prefers to call himself) is Board Certified in Internal Medicine, Endocrinology, and Metabolism and has a very large patient practice at the Endocrine Metabolic Medical Center in Palo Alto, California.  Dr. Joe is a pioneer in the potential of L-Arginine (the precursor for nitric oxide) to dramatically affect cardiovascular health.    Dr. Joe has used his nutritional formulation on over 7,000 patients of which approximately 80% are diabetics.  Because of Dr. Joe’s remarkable track record of less than 1% hospital admissions in over 15 plus years the American Diabetes Association named him the 2008 Father of the Year.  Dr. Joe is the product formulator of the nutritional supplement ProArgi-9 Plus and helped in the design of this study.

Synergy WorldWide – ProArgi-9 Plus is manufactured and distributed by Synergy WorldWide.  They donated the product for this study but didn’t underwrite any of the costs for the study so that they could remain neutral in the study design and results.

Dan SwinDell – Dan helped bring all the parties together and helped to facilitate some of the logistics of this study.  He has an intimate knowledge of the study and its results.

Click on the player below to listen to Dan SwinDell provide additional details about this groundbreaking heart disease study!

[audio:http://www.vt-us.net/co-op/audio/dan-swindell.mp3]

Dr. Louis J. Ignarro – Dr. Ignarro did not participate in this study but his Nobel Prize winning research is at the heart of this study.  In 1998 Dr. Ignarro shared the Nobel Prize in Medicine with two other American scientists for the discovery of nitric oxide and how it is the master signaling molecule for the cardiovascular system. In 2008, the American Heart Association selected Dr. Ignarro as a 2008 Distinguished Scientist.  Dr. Ignarro firmly believes that the proper use of nitric oxide can significantly improve the health of most cells and make a major impact on reducing the risk of heart disease.

Video Interviews About This Study

Angelo Cici – Angelo was a patient at the High Desert Heart Institute who was invited to participate in this study because of significant cardiovascular issues.  Angelo worked for Litton Industries as a Director of Product Support that oversaw 100 subsidiary companies.  On December 20, 2008 he experienced a massive heart failure with simultaneous renal failure, congestive heart failure and a pacemaker failure. His life was saved in the emergency room but then he spent the next several weeks in and out of the hospital in an effort to stabilize his health.  As Angelo describes it, “I was so weak I couldn’t even open a bottle of water by myself and I had decided, I had had enough.  I told the nurses I wanted all the IV’s removed and I just wanted to go home and die.” Needless to say Angelo didn’t die and he feels “like I’m 40 years old again!”

It’s with great honor and pleasure that we are able to bring you an extensive video interview with Angelo Cici.  This interview was conducted by John Hewlett of the ComoCardio Institute. It’s a fascinating look at how a man’s life was not just saved but returned to a vibrant and healthy lifesyle.  Enjoy the 2-part video:

Angelo Cici Interview – Part 1

Angelo Cici Interview – Part 2

Nurses Interview – The following video contains a short overview of this study, a short audio interview with Dr. Siva Arunasalam (the Founder and Director of the High Desert Heart Institute), and a short exchange between John Hewlett and two of the medical assistants who directly interacted with the patients of this study.  Again, we would like to thank John Hewlett and the ComoCardio Institute for allowing us to present this video to you.

Dr. Siva Arunasalam Interview – On Saturday, January 23, 2010 Dr. Siva Arunasalam, the Founder and Director of the High Desert Heart Institute gave his first public presentation of the groundbreaking results from the High Desert Heart Institute Study.  This study evaluated the effects of the nutritional supplement ProArgi-9 Plus on the health of 33 congestive heart failure patients.  The results of the study were “remarkable” in how a proper L-arginine and L-citrulline combination, with other heart healthy ingredients, can make positive changes in the cardiovascular system.

During the weekend event, John Hewlett of the ComoCardio Institute conducted a 15 minute video interview with Dr. Siva. We would like to thank John for allowing us to present this video to you.

The “remarkable” results of the High Desert Heart Institute Study have already impacted the treatment protocols at the High Desert Heart Institute!  It is amazing how the cardiovascular system can improve when the endothelial cells that line all of the cardiovascular system are properly cared for and nourished.  This process significantly improves their ability to properly create nitric oxide, the master signaling molecule of the cardiovascular system.

Remember, even though there are new methods being developed to help repair the cardiovascular system, always work with a qualified medical professional.

ProArgi-9 Plus Can Benefit Your Cardiovascular System

ProArgi-9 Plus is a clinically proven L-arginine / L-citrulline nutritional supplement designed to help repair your endothelial cells so that they can properly produce nitric oxide. The product formulator for ProArgi-9 Plus is Dr. J. Joseph Prendergast who incorporated Nobel Prize winning science, with cutting edge vascular research, to develop a clinically proven, natural supplement that has benefited thousands of his patients and tens of thousands of people around the world.